PTGIR Products
PTGIR is a member of the G protein-coupled receptor family 1 and has been shown to be a receptor for prostacyclin (prostaglandin I2 or PGI2). Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to PTGIR.
11 results for "PTGIR" in Products
11 results for "PTGIR" in Products
PTGIR Products
PTGIR is a member of the G protein-coupled receptor family 1 and has been shown to be a receptor for prostacyclin (prostaglandin I2 or PGI2). Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to PTGIR.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: PTGIR AntibodyBSA Free [NBP2-93654]](https://resources.bio-techne.com/images/products/PTGIR-Antibody-Western-Blot-NBP2-93654-img0003.jpg "Western Blot: PTGIR AntibodyBSA Free [NBP2-93654]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #4B10 |
| Applications: | IHC, WB, ELISA |
![Western Blot: PTGIR Antibody (4B10) [H00005739-M01]](https://resources.bio-techne.com/images/products/PTGIR-Antibody-4B10-Western-Blot-H00005739-M01-img0009.jpg "Western Blot: PTGIR Antibody (4B10) [H00005739-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2A7 |
| Applications: | WB, ELISA |
![Western Blot: PTGIR Antibody (2A7) [H00005739-M02]](https://resources.bio-techne.com/images/products/PTGIR-Antibody-2A7-Western-Blot-H00005739-M02-img0003.jpg "Western Blot: PTGIR Antibody (2A7) [H00005739-M02]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB |
![Western Blot: PTGIR Overexpression Lysate [NBL1-14939]](https://resources.bio-techne.com/images/products/Prostaglandin-I2-Receptor-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14939-img0002.jpg "Western Blot: PTGIR Overexpression Lysate [NBL1-14939]")
| Applications: | ELISA |
| Applications: | ELISA |
Potent prostacyclin (PGI2) analog
| Chemical Name: | 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid |
| Purity: | ≥98% (HPLC) |
Endogenous IP receptor agonist
| Alternate Names: | Prostaglandin I2,Prostacyclin |
| Chemical Name: | (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt |
| Purity: | ≥99% (HPLC) |
