RAB37: Proteins and Enzymes

Belonging to the small GTPase superfamily/ Rab family, RAB37 is involved with protein transport and small GTPase mediated signal transduction. Being a critical regulator of vesicular fusion and trafficking, Rab proteins are low molecular mass GTPases. Similarly, the molecular functions of these proteins include protein and GTP binding. RAB37 interacts with RAB5A, RIMS1, EWSR1, DTX4 and PCSK5. Diseases associated with RAB37 include renal cell carcinoma, lung cancer, hemophagocytic lymphohistiocytosis, Crohn's disease, psoriasis and neuronitis.