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RhoGAP Products

The p190 Rho GTPase activating protein RhoGAP) family includes two closely related proteins, p190-A and p190-B. p190-B contains an N-terminal GTPase domain and a C-terminal Rho-GAP domain (1). p190-B can be directly phosphorylated on a single identified tyrosine residue by the activated insulin and IGF-1 receptors. This phosphorylation causes p190-B to translocate to the lipid rafts of the plasma membrane, where it can facilitate the inactivation of the Rho GTPase. P190-B also has been shown to be tyrosine phosphorylated by c-Src and v-Src. Additionall; the GAP domain of p190-B as shown to attenuate signal-transducing activity of Rac, Rho and CDC42 (2-3).
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11 results for "RhoGAP" in Products

11 results for "RhoGAP" in Products

RhoGAP Products

The p190 Rho GTPase activating protein RhoGAP) family includes two closely related proteins, p190-A and p190-B. p190-B contains an N-terminal GTPase domain and a C-terminal Rho-GAP domain (1). p190-B can be directly phosphorylated on a single identified tyrosine residue by the activated insulin and IGF-1 receptors. This phosphorylation causes p190-B to translocate to the lipid rafts of the plasma membrane, where it can facilitate the inactivation of the Rho GTPase. P190-B also has been shown to be tyrosine phosphorylated by c-Src and v-Src. Additionall; the GAP domain of p190-B as shown to attenuate signal-transducing activity of Rac, Rho and CDC42 (2-3).
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Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: WB, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, IP
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, IP
Reactivity: Human, Mouse
Applications: IHC
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB, IP
Reactivity: Human, Mouse
Applications: AC
Applications: AC
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