Serpin E1/PAI-1 Products
Serpin E1, also known as Plasminogen Activator Inhibitor-1 (PAI-1), is the primary inhibitor of urokinase-type and tissue-type plasminogen activators (uPA and tPA) which convert Plasminogen to Plasmin. The PA-Plasmin system is involved in fibrinolysis, tissue fibrosis, angiogenesis, wound healing, tumor cell invasion and metastasis, and obesity. Serpin E1 can promote clot formation, arterial re-endothelialization, and neointima formation while protecting against vascular intima thickening. It binds Vitronectin and inhibits vascular smooth muscle cell and endothelial cell adhesion, proliferation, and motility. Serpin E1 binds and induces the LRP-dependent internalization of cell surface complexes containing uPA, uPAR, and Integrin alpha V beta 3. Serpin E1 secretion is upregulated during inflammation, physical injury, and exposure to Angiotensin II.
183 results for "Serpin E1/PAI-1" in Products
183 results for "Serpin E1/PAI-1" in Products
Serpin E1/PAI-1 Products
Serpin E1, also known as Plasminogen Activator Inhibitor-1 (PAI-1), is the primary inhibitor of urokinase-type and tissue-type plasminogen activators (uPA and tPA) which convert Plasminogen to Plasmin. The PA-Plasmin system is involved in fibrinolysis, tissue fibrosis, angiogenesis, wound healing, tumor cell invasion and metastasis, and obesity. Serpin E1 can promote clot formation, arterial re-endothelialization, and neointima formation while protecting against vascular intima thickening. It binds Vitronectin and inhibits vascular smooth muscle cell and endothelial cell adhesion, proliferation, and motility. Serpin E1 binds and induces the LRP-dependent internalization of cell surface complexes containing uPA, uPAR, and Integrin alpha V beta 3. Serpin E1 secretion is upregulated during inflammation, physical injury, and exposure to Angiotensin II.
| Sensitivity: | 0.142 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.312 - 20 ng/mL (Cell Culture Supernates, Cell Lysates, EDTA Plasma, Heparin Plasma, Citrate Plasma, CTAD Plasma) |
| Sensitivity: | 0.046 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
Simple Plex Human Serpin E1/PAI-1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD06, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Serpin E1/PAI-1 AntibodyBSA Free [NBP1-19773]](https://resources.bio-techne.com/images/products/Serpin-E1-PAI-1-Antibody-Western-Blot-NBP1-19773-img0005.jpg "Western Blot: Serpin E1/PAI-1 AntibodyBSA Free [NBP1-19773]")
| Source: | Sf 21 (stably transfected) |
| Accession #: | P05121 |
| Applications: | InhibAct |
| Assay Range: | 0.312 - 20 ng/mL |
| Applications: | ELISA |
| Assay Range: | 9.38 - 600 pg/mL |
| Applications: | ELISA |
Control for use with Human Serpin E1/PAI-1 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1D5 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
![Western Blot: Serpin E1/PAI-1 Antibody (1D5)BSA Free [NBP2-37532]](https://resources.bio-techne.com/images/products/Serpin-E1-PAI-1-Antibody-1D5-Western-Blot-NBP2-37532-img0003.jpg "Western Blot: Serpin E1/PAI-1 Antibody (1D5)BSA Free [NBP2-37532]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Serpin E1/PAI-1 Antibody [NBP2-13298]](https://resources.bio-techne.com/images/products/Serpin-E1-PAI-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-13298-img0004.jpg "Immunocytochemistry/ Immunofluorescence: Serpin E1/PAI-1 Antibody [NBP2-13298]")
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
For use with catalog number DSE100
| Applications: | ELISA, Ctrl |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: Serpin E1/PAI-1 Antibody [NB100-1498]](https://resources.bio-techne.com/images/products/Serpin-E1-PAI-1-Antibody-Western-Blot-NB100-1498-img0011.jpg "Western Blot: Serpin E1/PAI-1 Antibody [NB100-1498]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1C5 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: Serpin E1/PAI-1 Antibody (1C5)BSA Free [NBP2-59495]](https://resources.bio-techne.com/images/products/Serpin-E1-PAI-1-Antibody-1C5-Western-Blot-NBP2-59495-img0001.jpg "Western Blot: Serpin E1/PAI-1 Antibody (1C5)BSA Free [NBP2-59495]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1779 |
| Applications: | WB, ICC/IF, Flow, IP |
| Applications: | ELISA |
| Applications: | AC |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #10C3 |
| Applications: | IHC, WB, ELISA |
| Applications: | ELISA |
| Applications: | AC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Applications: | ELISA |
![ELISA: Human Serpin E1/PAI-1 ELISA Kit (Colorimetric) [NBP1-83740]](https://resources.bio-techne.com/images/products/Human-Serpin-E1-PAI-1-ELISA-Kit-Colorimetric-ELISA-NBP1-83740-img0001.jpg "ELISA: Human Serpin E1/PAI-1 ELISA Kit (Colorimetric) [NBP1-83740]")
| Applications: | ELISA |
