Siglec-9 Products
Siglecs are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal, Ig-like V-type domain that mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains (2 to 17), a single transmembrane region, and a cytoplasmic tail. The siglecs can be broadly classified into two subgroups: Siglecs-1, -2, and -4, and a Siglec-3/CD33-related subgroup (Siglecs-3, and -5 through -13 in primates) defined by sequence similarity and clustered gene localization. They are widely expressed on hematopoietic cells, often in a cell-type-specific manner, and Siglec-4/MAG is a myelin component in Schwann cells and oligodendrocytes. Their ligands, sialic acids, are negatively charged monosaccharides found on cell-surface glycoproteins and glycolipids. Although Siglec functions continue to be defined, most have intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIM), implicating them in the suppression of immunoreceptor signaling. They may also participate in cell/cell interactions or act as receptors for the entry of viral or bacterial pathogens.
101 results for "Siglec-9" in Products
101 results for "Siglec-9" in Products
Siglec-9 Products
Siglecs are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal, Ig-like V-type domain that mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains (2 to 17), a single transmembrane region, and a cytoplasmic tail. The siglecs can be broadly classified into two subgroups: Siglecs-1, -2, and -4, and a Siglec-3/CD33-related subgroup (Siglecs-3, and -5 through -13 in primates) defined by sequence similarity and clustered gene localization. They are widely expressed on hematopoietic cells, often in a cell-type-specific manner, and Siglec-4/MAG is a myelin component in Schwann cells and oligodendrocytes. Their ligands, sialic acids, are negatively charged monosaccharides found on cell-surface glycoproteins and glycolipids. Although Siglec functions continue to be defined, most have intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIM), implicating them in the suppression of immunoreceptor signaling. They may also participate in cell/cell interactions or act as receptors for the entry of viral or bacterial pathogens.
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Source: | NS0 |
Accession #: | Q9Y336 |
Applications: | BA |
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, CyTOF-ready, ICC |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, ICC |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2 Monoclonal Clone #MM0552-6K12 |
Applications: | WB, B/N |
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | WB, Flow, CyTOF-ready, Neut |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Simple Plex Human Siglec-9 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Reactivity: | Human, Canine, Monkey |
Details: | Mouse IgG1 Monoclonal Clone #OTI1D9 |
Applications: | IHC, WB |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Source: | HEK293 |
Accession #: | XP_005590140.2 |
Applications: | BA |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Control for use with Human Siglec-9 Simple Plex Cartridge Kit
Applications: | Ctrl, Simple Plex |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #191240 |
Applications: | Flow |
Applications: | AC |
Clone 191240 was used by HLDA to establish CD designation
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #191240 |
Applications: | WB, ELISA, Flow, CyTOF-ready, B/N, +2 More |