Smad5 Products
Smads are a family of intracellular proteins that mediate signaling by members of the TGF-beta superfamily. Smads are divided into three distinct subgroups based on their different roles in TGF-beta family signal transduction: R-Smads (receptor-regulated), Co-Smads (common partner), and I-Smads (inhibitory). In general, activation of TGF-beta superfamily serine/threonine kinase receptors leads to the phosphorylation of R-Smads (Smads1, 2, 3, 5, and 8). This is followed by recruitment of the Co-Smad (Smad-4) into an R-Smad/Co-Smad complex that translocates to the nucleus to regulate gene expression. I-Smads (Smad6 and Smad7) antagonize this signaling pathway by preventing R-Smads from interacting with the receptor, or by competing with Co-Smads for the generation of R-Smad/Co-Smad complexes.
25 results for "Smad5" in Products
25 results for "Smad5" in Products
Smad5 Products
Smads are a family of intracellular proteins that mediate signaling by members of the TGF-beta superfamily. Smads are divided into three distinct subgroups based on their different roles in TGF-beta family signal transduction: R-Smads (receptor-regulated), Co-Smads (common partner), and I-Smads (inhibitory). In general, activation of TGF-beta superfamily serine/threonine kinase receptors leads to the phosphorylation of R-Smads (Smads1, 2, 3, 5, and 8). This is followed by recruitment of the Co-Smad (Smad-4) into an R-Smad/Co-Smad complex that translocates to the nucleus to regulate gene expression. I-Smads (Smad6 and Smad7) antagonize this signaling pathway by preventing R-Smads from interacting with the receptor, or by competing with Co-Smads for the generation of R-Smad/Co-Smad complexes.
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SY09-03 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Human, Rat |
Details: | Mouse IgG1 Monoclonal Clone #3H9 |
Applications: | IHC, WB, ELISA, ICC/IF, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SR2030 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #3A10 |
Applications: | WB, ELISA, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #2D7 |
Applications: | WB, ELISA, ICC/IF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #SR1930 |
Applications: | WB, ICC/IF |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #4F10 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #5E12 |
Applications: | WB, ELISA |
Applications: | WB, ELISA, MA, AP |
Applications: | WB, ELISA, MA, AP, PAGE |
Recombinant monoclonal antibody expressed in HEK293F cells
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #3A9 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #1C1 |
Applications: | WB, ELISA |
Recombinant monoclonal antibody expressed in HEK293F cells
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2G11 |
Applications: | IHC, ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #4D4X8 |
Applications: | WB, ELISA |
Applications: | WB |
Applications: | WB |
Reactivity: | Human, Rat |
Details: | Rabbit IgG Monoclonal Clone #5W8T5 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #8F4B10 |
Applications: | WB, ELISA |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #1X5G9 |
Applications: | WB, ELISA, IP |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #2Q7T2 |
Applications: | WB, ELISA |
Applications: | AC |