Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor-binding domain.
The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
Products:
268 results for "Spike RBD" in Products
268 results for "Spike RBD" in Products
Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor-binding domain.
The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
Products:
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2b Monoclonal Clone #1042425 |
| Applications: | Flow |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG1 Monoclonal Clone #1035753 |
| Applications: | ELISA, Block |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2a Monoclonal Clone #1035740 |
| Applications: | ELISA, Block |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2b Monoclonal Clone #1035709 |
| Applications: | ELISA, Block |
HEK293 Expressed, High ACE-2 Binding
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
Delta Variant (India) L452R T478K
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2a Monoclonal Clone #1035423 |
| Applications: | IHC, Block |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2b Monoclonal Clone #1034522 |
| Applications: | WB |
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2b Monoclonal Clone #1034515 |
| Applications: | WB, Simple Western |
N439K, E484K
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
Biotinylated via Amines
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
Biotinylated
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA, BA |
Mammalian CHO Cell Expressed, High ACE-2 Binding
| Source: | CHO |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2a Monoclonal Clone #1042425 |
| Applications: | WB, Flow, ICC |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2b Monoclonal Clone #1049132 |
| Applications: | ICC |
His-tag
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
Val367Phe Point Mutation
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
N501Y Mutation found in Alpha, Beta, and Gamma Variants
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
Tn5 Insect Cell Expressed, High ACE-2 Binding Analyzed by SEC-MALS
| Source: | T. ni (baculovirus) |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG2a Monoclonal Clone #1049621 |
| Applications: | Block, ICC, Neut |
| Reactivity: | SARS-CoV-2 |
| Details: | Mouse IgG1 Monoclonal Clone #1049417 |
| Applications: | Block, ICC, Neut |
| Source: | HEK293 |
| Accession #: | YP_009724390.1 |
| Applications: | BA |
