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T-bet/TBX21 Products

T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.

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181 results for "T-bet/TBX21" in Products

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181 results for "T-bet/TBX21" in Products

T-bet/TBX21 Products

T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.

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Applications: WB, ICC, ICFlow
Reactivity: Human
Applications: CyTOF-ready, ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ICC/IF, IP
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human
Applications: IHC, WB, ICC/IF, Flow, IP
Reactivity: Human

Recombinant Monoclonal

Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse
Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB, Flow, IP
Reactivity: Human, Mouse, Rhesus Macaque
Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
Applications: ICFlow
Reactivity: Human
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