T-bet/TBX21 Products
T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.
181 results for "T-bet/TBX21" in Products
181 results for "T-bet/TBX21" in Products
T-bet/TBX21 Products
T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | WB, ICC, ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | CyTOF-ready, ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #39D |
Applications: | IHC, WB, ICC/IF, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Recombinant Monoclonal
Reactivity: | Human |
Details: | Rabbit Monoclonal Clone #BLR110H |
Applications: | IHC, WB, ICC/IF, Flow, IP |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #JE60-20 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human, Mouse, Rhesus Macaque |
Details: | Mouse IgG1 kappa Monoclonal Clone #4B10 |
Applications: | WB, Flow, IP |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Recombinant Monoclonal Antibody.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525831 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #525803 |
Applications: | ICFlow |