T-bet/TBX21 Products
T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.
161 results for "T-bet/TBX21" in Products
161 results for "T-bet/TBX21" in Products
T-bet/TBX21 Products
T-box expressed in T cells (T-bet), also known as T-box transcription factor TBX21, is a 62 kDa member of the T-box family of transcription factors and the Tbr1 subfamily. Human T-bet is 535 amino acids in length and contains a T-box DNA binding domain (aa 136-327). Human T-bet shares 88% aa sequence identity with mouse T-bet. T-bet is a nuclear protein highly apparent in Th1-cells. Northern blot analysis revealed that it is also expressed in lung, thymus and spleen. Functionally, T-bet controls the expression of the Th1 cytokine, IFN-gamma, and initiates Th1 lineage development from naive Th precursor cells by both activating Th1 genetic programs and by repressing the opposing Th2 programs.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | WB, ICC, ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #39D |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: T-bet/TBX21 Antibody (39D)BSA Free [NBP1-43299]](https://resources.bio-techne.com/images/products/T-bet-TBX21-Antibody-39D-Western-Blot-NBP1-43299-img0004.jpg "Western Blot: T-bet/TBX21 Antibody (39D)BSA Free [NBP1-43299]")
| Reactivity: | Human, Mouse, Rhesus Macaque |
| Details: | Mouse IgG1 kappa Monoclonal Clone #4B10 |
| Applications: | WB, Flow, IP |
![Western Blot: T-bet/TBX21 Antibody (4B10)BSA Free [NBP1-43298]](https://resources.bio-techne.com/images/products/T-bet-TBX21-Antibody-4B10-Western-Blot-NBP1-43298-img0002.jpg "Western Blot: T-bet/TBX21 Antibody (4B10)BSA Free [NBP1-43298]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | CyTOF-ready, ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525831 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #525803 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: T-bet/TBX21 AntibodyBSA Free [NBP2-41235]](https://resources.bio-techne.com/images/products/T-bet-TBX21-Antibody-Western-Blot-NBP2-41235-img0001.jpg "Western Blot: T-bet/TBX21 AntibodyBSA Free [NBP2-41235]")
Recombinant Monoclonal
| Reactivity: | Human |
| Details: | Rabbit Monoclonal Clone #BLR110H |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Immunoprecipitation: T-bet/TBX21 Antibody (BLR110H) [NBP3-14699]](https://resources.bio-techne.com/images/products/T-bet-TBX21-Antibody-Immunoprecipitation-NBP3-14699-img0001.jpg "Immunoprecipitation: T-bet/TBX21 Antibody (BLR110H) [NBP3-14699]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: T-bet/TBX21 Antibody [NBP2-20583]](https://resources.bio-techne.com/images/products/T-bet-TBX21-Antibody-Western-Blot-NBP2-20583-img0003.jpg "Western Blot: T-bet/TBX21 Antibody [NBP2-20583]")