TANK: Lysates
Tumor Necrosis Factor Receptor-associated Factor (TRAF) Family Member-associated NF-kappa B Activator (TANK) is a 425 amino acid protein with a predicted molecular mass of 48 kDa. Three isoforms of TANK have been identified in humans. Mouse and rat TANK share 82% and 81% amino acid sequence identity with the human protein, respectively. TANK is ubiquitously expressed and maintains TRAF-1, TRAF-2, and TRAF-3 proteins in their latent states by binding to their TRAF-c domains. TANK may function as an adaptor molecule in multiple antiviral pathways including those activated by TLR3 and TLR4. TANK is also a negative regulator of osteoclastogenesis and thereby modulates bone homeostasis.
1 result for "TANK Lysates" in Products
1 result for "TANK Lysates" in Products
TANK: Lysates
Tumor Necrosis Factor Receptor-associated Factor (TRAF) Family Member-associated NF-kappa B Activator (TANK) is a 425 amino acid protein with a predicted molecular mass of 48 kDa. Three isoforms of TANK have been identified in humans. Mouse and rat TANK share 82% and 81% amino acid sequence identity with the human protein, respectively. TANK is ubiquitously expressed and maintains TRAF-1, TRAF-2, and TRAF-3 proteins in their latent states by binding to their TRAF-c domains. TANK may function as an adaptor molecule in multiple antiviral pathways including those activated by TLR3 and TLR4. TANK is also a negative regulator of osteoclastogenesis and thereby modulates bone homeostasis.
| Applications: | WB |
![Western Blot: TANK Overexpression Lysate [NBL1-16696]](https://resources.bio-techne.com/images/products/TANK-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-16696-img0002.jpg "Western Blot: TANK Overexpression Lysate [NBL1-16696]")