Tankyrase Inhibitors Products
Tankyrase 1, also known as TNKS, TANK1, and PARP5A, is a ubiquitously expressed member of the PARP family of proteins. Its ribosylation activity inhibits TRF1, a regulator of telomere length, leading to chromosomal lengthening. Tankyrase 1 also activates the Wnt signaling pathway by promoting Axin-1 and -2 degradation followed by beta-Catenin activation.
1 result for "Tankyrase Inhibitors" in Products
1 result for "Tankyrase Inhibitors" in Products
Tankyrase Inhibitors Products
Tankyrase 1, also known as TNKS, TANK1, and PARP5A, is a ubiquitously expressed member of the PARP family of proteins. Its ribosylation activity inhibits TRF1, a regulator of telomere length, leading to chromosomal lengthening. Tankyrase 1 also activates the Wnt signaling pathway by promoting Axin-1 and -2 degradation followed by beta-Catenin activation.
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
