TBC1D4 Products
AS160, also known as TBC1D4, is a 160 kDa Akt substrate that plays a critical role in regulating insulin-stimulated exocytosis of glucose transporter GLUT4. AS-160 contains a Rab GTPase-activating protein domain (GAP), suggesting its potential role in membrane trafficking. Insulin-stimulated phosphorylation of AS160 on threonine 642 is critical for mediating GLUT4 translocation in fat and muscle cells, via inactivation of Rab GAP function. Phosphorylation of Thr642 is also important in mediating TBC1D4 redistribution from low density microsomes to the cytosol in adipocytes.
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72 results for "TBC1D4" in Products
72 results for "TBC1D4" in Products
TBC1D4 Products
AS160, also known as TBC1D4, is a 160 kDa Akt substrate that plays a critical role in regulating insulin-stimulated exocytosis of glucose transporter GLUT4. AS-160 contains a Rab GTPase-activating protein domain (GAP), suggesting its potential role in membrane trafficking. Insulin-stimulated phosphorylation of AS160 on threonine 642 is critical for mediating GLUT4 translocation in fat and muscle cells, via inactivation of Rab GAP function. Phosphorylation of Thr642 is also important in mediating TBC1D4 redistribution from low density microsomes to the cytosol in adipocytes.
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Applications: WB, ICC/IF, Flow
Reactivity:
Human,
Mouse,
Rat
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI5E6 |
| Applications: | WB, ICC/IF, Flow |
![Western Blot: TBC1D4 Antibody (OTI5E6) [NBP2-00597]](https://resources.bio-techne.com/images/products/TBC1D4-Antibody-5E6-Western-Blot-NBP2-00597-img0004.jpg "Western Blot: TBC1D4 Antibody (OTI5E6) [NBP2-00597]")
Applications: IHC, WB, ELISA
Reactivity:
Human
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: TBC1D4 Antibody [NB100-57094]](https://resources.bio-techne.com/images/products/TBC1D4-Antibody-Western-Blot-NB100-57094-img0002.jpg "Western Blot: TBC1D4 Antibody [NB100-57094]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1272 |
| Applications: | WB |
Applications: WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE60-97 |
| Applications: | WB, ICC/IF |
![TBC1D4 [p Thr642] Antibody (JE60-97)](https://resources.bio-techne.com/images/products/nbp3-32749_rabbit-tbc1d4-p-thr642-mab-je60-97-278202415212425.jpg "Western Blot: TBC1D4 [p Thr642] Antibody (JE60-97) [NBP3-32749]")
Applications: IHC, WB, ELISA
Reactivity:
Human,
Mouse,
Rat
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TBC1D4 Antibody [NBP2-38460]](https://resources.bio-techne.com/images/products/TBC1D4-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-38460-img0005.jpg "Immunocytochemistry/ Immunofluorescence: TBC1D4 Antibody [NBP2-38460]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: TBC1D4 [p Ser588] AntibodyAzide and BSA Free [NBP3-05451]](https://resources.bio-techne.com/images/products/TBC1D4-[p-Ser588]-Antibody-Western-Blot-NBP3-05451-img0001.jpg "Western Blot: TBC1D4 [p Ser588] AntibodyAzide and BSA Free [NBP3-05451]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
![Immunohistochemistry: TBC1D4 Antibody - BSA Free [NBP2-81935]](https://resources.bio-techne.com/images/products/TBC1D4-Antibody-Immunohistochemistry-NBP2-81935-img0001.jpg "Immunohistochemistry: TBC1D4 Antibody - BSA Free [NBP2-81935]")
Applications: WB, ELISA, ICC/IF
Reactivity:
Mouse,
Rat
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Applications: | WB |
![Western Blot: TBC1D4 Overexpression Lysate [NBP2-07277]](https://resources.bio-techne.com/images/products/TBC1D4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07277-img0001.jpg "Western Blot: TBC1D4 Overexpression Lysate [NBP2-07277]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: TBC1D4 Antibody [NBP2-38880]](https://resources.bio-techne.com/images/products/TBC1D4-Antibody-Immunohistochemistry-Paraffin-NBP2-38880-img0002.jpg "Immunohistochemistry-Paraffin: TBC1D4 Antibody [NBP2-38880]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Applications: | AC |
| Applications: | AC |
Applications: WB, ICC/IF, Flow, CyTOF-ready
Reactivity:
Human,
Mouse,
Rat
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI5E6 |
| Applications: | WB, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |