TCL6: Lysates

The function of this protein has not yet been defined; however, this protein may play a role which is similar to or complementary to other T-cell leukemia/lymphoma proteins during early embrogenesis. The association of this gene with T-cell leukemia chromosome translocations implicates this gene as a candidate for leukemogenesis. Complex alternative splicing of this gene results in multiple transcript variants, six of which have been fully described. Among these described variants, four different open reading frames have been identified; three of the six variants code for an identical product. [provided by RefSeq]. Transcript Variant: This variant (TCL6a3) lacks exons 1 through 4 and contains exons 5a, 6b, 6d, 7a, 8a, and 12. This variant contains the same 141-amino acid open reading frame as variants a1 and a2.