TGF-beta Products
TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.
157 results for "TGF-beta" in Products
157 results for "TGF-beta" in Products
TGF-beta Products
TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.
| Reactivity: | Multi-Species |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | IHC, ELISA, ICC/IF, ELISA(Cap) |
![Immunocytochemistry/ Immunofluorescence: TGF-beta Antibody (1D11.16.8) - BSA Free [NBP2-45137]](https://resources.bio-techne.com/images/products/TGF-beta-Antibody-1D11-16-8-BSA-Free-Immunocytochemistry-Immunofluorescence-NBP2-45137-img0002.jpg "Immunocytochemistry/ Immunofluorescence: TGF-beta Antibody (1D11.16.8) - BSA Free [NBP2-45137]")
TGF-β receptor 2 (TβR2) binding peptide; disrupts the TGF-β/TβR2 interaction
| Purity: | ≥95% (HPLC) |
Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
| Chemical Name: | 3'-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | WB, ELISA, ICC/IF, Func, B/N |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TGFB/510 |
| Applications: | ELISA, Func |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #TGFB/7240 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #TGFB/7240 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #TGFB/7230 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #TGFB/7230 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TGFB/510 |
| Applications: | ELISA, Func |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | WB, ELISA, ICC/IF, Func |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #TGFB/7240 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | WB, ELISA, ICC/IF, Func |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TGFB/510 |
| Applications: | ELISA, Func |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | WB, ELISA, ICC/IF, Func |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #TGFB/510 |
| Applications: | ELISA, Func |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #TGFB/7240 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | WB, ELISA, ICC/IF, Func |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #TGFB/7240 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #TGFB/7230 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #TGFB/7230 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #TGFB/7230 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +2 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1D11.16.8 |
| Applications: | WB, ELISA, ICC/IF, Func |
| Reactivity: | Human |
| Details: | Mouse IgG2 kappa Monoclonal Clone #TGFB/7230 |
| Applications: | IHC |