TIM-1/KIM-1/HAVCR Products
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
170 results for "TIM-1/KIM-1/HAVCR" in Products
170 results for "TIM-1/KIM-1/HAVCR" in Products
TIM-1/KIM-1/HAVCR Products
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Sensitivity: | 0.046 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Urine) |
| Sensitivity: | 2.18 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.81 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Reactivity: | Human, Mouse, Rat, Porcine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ELISA, KD, +1 More |
![Western Blot: TIM-1/KIM-1/HAVCR AntibodyBSA Free [NBP1-76701]](https://resources.bio-techne.com/images/products/TIM-1-KIM-1-HAVCR-Antibody-Western-Blot-NBP1-76701-img0016.jpg "Western Blot: TIM-1/KIM-1/HAVCR AntibodyBSA Free [NBP1-76701]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Dual ISH-IHC |
Clone 219211 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219211 |
| Applications: | WB, Flow, IHC, CyTOF-ready |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #222414 |
| Applications: | WB, Flow |
| Sensitivity: | 2.74 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.81 - 500 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: TIM-1/KIM-1/HAVCR Antibody [NB100-56421]](https://resources.bio-techne.com/images/products/TIM-1-KIM-1-HAVCR-Antibody-Western-Blot-NB100-56421-img0003.jpg "Western Blot: TIM-1/KIM-1/HAVCR Antibody [NB100-56421]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #511227 |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #222414 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | AAC39862 |
| Applications: | BA |
Clone 219211 was used by HLDA to establish CD designation
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219211 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | O54947 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #3B3 |
| Applications: | IHC, ELISA, ICC/IF, Flow, Func, +2 More |
![ELISA: TIM-1/KIM-1/HAVCR Antibody (3B3) - Chimeric - Azide and BSA Free [NBP2-81119]](https://resources.bio-techne.com/images/products/TIM-1-KIM-1-HAVCR-Antibody-3B3-ELISA-NBP2-81119-img0001.jpg "ELISA: TIM-1/KIM-1/HAVCR Antibody (3B3) - Chimeric - Azide and BSA Free [NBP2-81119]")