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ULBP-1 Products

ULBP-1, -2, and -3 were originally identified as ligands for the human cytomegalovirus glycoprotein UL16 and designated UL16-binding proteins (ULBP). These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. ULBP-1, -2, and -3 are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells.

MULT1 (mouse UL16-binding protein-like Transcript 1) is a 53 kDa, MHC Class I-like molecule that belongs to the mouse family of NKG2D ligands. It is a type I transmembrane glycoprotein that is synthesized as a 334 amino acid (aa) precursor. It contains a 25 aa signal sequence, a 186 aa extracellular region, a 19 aa transmembrane segment and a 104 aa cytoplasmic tail. The extracellular region contains an alpha-1 and alpha-2 like domain with two intrachain disulfide bonds.

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110 results for "ULBP-1" in Products

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110 results for "ULBP-1" in Products

ULBP-1 Products

ULBP-1, -2, and -3 were originally identified as ligands for the human cytomegalovirus glycoprotein UL16 and designated UL16-binding proteins (ULBP). These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. ULBP-1, -2, and -3 are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells.

MULT1 (mouse UL16-binding protein-like Transcript 1) is a 53 kDa, MHC Class I-like molecule that belongs to the mouse family of NKG2D ligands. It is a type I transmembrane glycoprotein that is synthesized as a 334 amino acid (aa) precursor. It contains a 25 aa signal sequence, a 186 aa extracellular region, a 19 aa transmembrane segment and a 104 aa cytoplasmic tail. The extracellular region contains an alpha-1 and alpha-2 like domain with two intrachain disulfide bonds.

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Applications: Flow, Block, CyTOF-ready
Reactivity: Human
Applications: Flow, CyTOF-ready
Reactivity: Mouse
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB, Block
Reactivity: Human
Applications: Flow
Reactivity: Mouse
Applications: IHC, WB, Flow, Func
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Mouse
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