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USAG1 Products

USAG1, also known as WISE, Ectodin, or SOSTDC1, is a secreted  glycoprotein of the sclerostin family. It binds and sequesters BMP-2, -4, -6, and -7, and it blocks LRP5 and LRP6 interaction with Wnt proteins. USAG1 co-localizes with BMP-7 in the developing and adult kidney, particularly in distal tubule epithelial cells. It is also found in ectodermal tissues such as tooth ameloblasts, osteoblasts, cells of the dermal papilla, mammary placode epithelium, and uterine lumenal epithelium. USAG1 coordinates BMP, Wnt, FGF, and Shh signals to regulate apoptosis during tooth and bone development.

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69 results for "USAG1" in Products

69 results for "USAG1" in Products

USAG1 Products

USAG1, also known as WISE, Ectodin, or SOSTDC1, is a secreted  glycoprotein of the sclerostin family. It binds and sequesters BMP-2, -4, -6, and -7, and it blocks LRP5 and LRP6 interaction with Wnt proteins. USAG1 co-localizes with BMP-7 in the developing and adult kidney, particularly in distal tubule epithelial cells. It is also found in ectodermal tissues such as tooth ameloblasts, osteoblasts, cells of the dermal papilla, mammary placode epithelium, and uterine lumenal epithelium. USAG1 coordinates BMP, Wnt, FGF, and Shh signals to regulate apoptosis during tooth and bone development.

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Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: BA
Applications: WB
Reactivity: Human
Applications: ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat
Applications: AC
Applications: WB
Reactivity: Human
Applications: WB
Catalog #: NBP3-40431
Applications: ELISA
Catalog #: NBP3-40432
Applications: ELISA
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
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