Wnt-3a Products
Wnt-3a is a secreted protein that is necessary for proper embryonic development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. It also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells. The post-translational glycosylation and acylation of Wnts are essential for their efficient secretion and biological activity, respectively. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta-catenin levels. As intracellular beta-catenin levels rise, beta-catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes.
95 results for "Wnt-3a" in Products
95 results for "Wnt-3a" in Products
Wnt-3a Products
Wnt-3a is a secreted protein that is necessary for proper embryonic development of the hippocampus, anterior-posterior patterning, somite development, and tailbud formation. It also promotes self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells. The post-translational glycosylation and acylation of Wnts are essential for their efficient secretion and biological activity, respectively. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta-catenin levels. As intracellular beta-catenin levels rise, beta-catenin binds to TCF/LEF transcription factors leading to expression of Wnt target genes.
| Source: | CHO |
| Accession #: | NP_149122 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | NP_149122.1 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P27467 |
| Applications: | BA |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
| Source: | CHO |
| Accession #: | NP_149122 |
| Applications: | BA, BA |
| Assay Range: | 156 - 10,000 pg/mL |
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | WB, CyTOF-ready, ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG1 Monoclonal Clone #930769 |
| Applications: | Neut |
| Source: | CHO |
| Accession #: | P27467 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #1E6G4 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: Wnt-3a Antibody (1E6G4)BSA Free [NBP2-52588]](https://resources.bio-techne.com/images/products/Wnt-3a-Antibody-1E6G4-Western-Blot-NBP2-52588-img0007.jpg "Western Blot: Wnt-3a Antibody (1E6G4)BSA Free [NBP2-52588]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Wnt-3a Antibody [NBP1-74183]](https://resources.bio-techne.com/images/products/Wnt-3a-Antibody-Western-Blot-NBP1-74183-img0009.jpg "Western Blot: Wnt-3a Antibody [NBP1-74183]")
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3A6 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Wnt-3a Antibody (3A6)BSA Free [NBP1-19050]](https://resources.bio-techne.com/images/products/Wnt-3a-Antibody-3A6-Western-Blot-NBP1-19050-img0007.jpg "Western Blot: Wnt-3a Antibody (3A6)BSA Free [NBP1-19050]")
| Source: | CHO |
| Accession #: | P27467 |
| Applications: | BA, BA |
endo-IWR 1 synthesized to Ancillary Material Grade
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #217804.2R |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #HL1911 |
| Applications: | WB |
Wnt pathway inhibitor
| Chemical Name: | 4-[4-(4-Methoxyphenyl)-5-[[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]thio]-4H-1,2,4-triazol-3-yl]-pyridine |
| Purity: | ≥99% (HPLC) |
