Inflammasomes Inhibitors: Small Molecules and Peptides
12 results for "Inflammasomes Inhibitors Small Molecules and Peptides" in Products
12 results for "Inflammasomes Inhibitors Small Molecules and Peptides" in Products
Inflammasomes Inhibitors: Small Molecules and Peptides
Cell-permeable, irreversible caspase inhibitor
| Chemical Name: | Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone |
| Purity: | ≥95% |
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
| Alternate Names: | CP-456773,MCC 950 |
| Chemical Name: | N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt |
| Purity: | ≥98% (HPLC) |
NLRP3 inhibitor; active in vivo
| Chemical Name: | 4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
NLRP3 inflammasome inhibitor
| Alternate Names: | JC121 |
| Chemical Name: | N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
| Chemical Name: | 3-(Methylsulfonyl)propanenitrile |
| Purity: | ≥98% |
E2 ubiquitin (Ub) conjugating enzymes inhibitor
| Chemical Name: | (2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile |
| Purity: | ≥99% |
NLRP3 inflammasome inhibitor
| Chemical Name: | (T4)-[2-Acetyl-4,4,4-trichloro-3-(imino-κN)butanamidito-κO]diphenylboron |
| Purity: | ≥98% |
Potent NLRP3 inflammasome inhibitor
| Chemical Name: | (T4)-[2-Acetyl-4,4,4-trichloro-N-cyclohexyl-3-(imino-κN)butanamidato-κO]diphenylboron |
| Purity: | ≥98% |
Caspase-1 and NLRP3 inflammasome inhibitor
| Chemical Name: | Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate |
| Purity: | ≥98% |
Irreversible NLRP3 inhibitor
| Chemical Name: | Ethyl 2-(2-chlorobenzyl)acrylate |
| Purity: | ≥98% |
Potent NLRP3 inflammasome inhibitor
| Chemical Name: | 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione |
| Purity: | ≥95% (HPLC) |
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
| Chemical Name: | 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic acid |
| Purity: | ≥98% (HPLC) |
