Raf-1 Products
Raf-1 is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. The activated Raf-1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the Serine/Threonine specific protein kinases ERK1 and ...
20 results for "Raf-1" in Products
20 results for "Raf-1" in Products
Raf-1 Products
Raf-1 is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. The activated Raf-1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the Serine/Threonine specific protein kinases ERK1 and ...
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #563002 |
| Applications: | WB, Simple Western, IHC |
Potent, selective c-Raf1 kinase inhibitor
| Chemical Name: | 3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #1H4 |
| Applications: | WB, ELISA, Func, KD |
![Western Blot: Raf-1 Antibody (1H4) [H00005894-M03]](https://resources.bio-techne.com/images/products/Raf-1-Antibody-1H4-Western-Blot-H00005894-M03-img0007.jpg "Western Blot: Raf-1 Antibody (1H4) [H00005894-M03]")
| Reactivity: | Bovine, Canine, Chicken, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_002880 |
| Applications: | BA |
| Reactivity: | Bovine, Canine, Chicken, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Raf-1 Antibody [H00005894-B01P]](https://resources.bio-techne.com/images/products/Raf-1-Antibody-Western-Blot-H00005894-B01P-img0004.jpg "Western Blot: Raf-1 Antibody [H00005894-B01P]")
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Raf-1 [p Ser301] Antibody [NB300-305]](https://resources.bio-techne.com/images/products/Raf1-[p-Ser301]-Antibody-Western-Blot-NB300-305-img0001.jpg "Western Blot: Raf-1 [p Ser301] Antibody [NB300-305]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #4G4 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
![Western Blot: Raf-1 Antibody (4G4)BSA Free [NBP2-37513]](https://resources.bio-techne.com/images/products/Raf-1-Antibody-4G4-Western-Blot-NBP2-37513-img0003.jpg "Western Blot: Raf-1 Antibody (4G4)BSA Free [NBP2-37513]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2182 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Raf-1 Antibody [NBP1-85462]](https://resources.bio-techne.com/images/products/Raf-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-85462-img0006.jpg "Immunocytochemistry/ Immunofluorescence: Raf-1 Antibody [NBP1-85462]")
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Raf-1 [p Ser642] Antibody [NB300-306]](https://resources.bio-techne.com/images/products/Raf-1-[p-Ser642]-Antibody-Western-Blot-NB300-306-img0001.jpg "Western Blot: Raf-1 [p Ser642] Antibody [NB300-306]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2181 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2183 |
| Applications: | WB |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
| Chemical Name: | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Applications: | AC |
Potent Raf kinase inhibitor
| Chemical Name: | 3-(1-Cyano-1-methylethyl)-N-[3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-methylphenyl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent BRAF and CRAF inhibitor
| Chemical Name: | N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide |
| Purity: | ≥98% (HPLC) |
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
| Chemical Name: | 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
| Applications: | ELISA |
