5-HT2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90322

Novus Biologicals, part of Bio-Techne
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NBP1-90322
NBP1-90322-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all 5-HT2B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TIHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGSRKDKALPNSGDETLMRRTSTIGKKSVQTISNEQRASKVL

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23584090)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for 5-HT2B Antibody

Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322]

Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322]

Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322] - Staining in human endometrium and skeletal muscle tissues . Corresponding HTR2B RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: 5-HT2B Antibody [NBP1-90322]

Immunocytochemistry/ Immunofluorescence: 5-HT2B Antibody [NBP1-90322]

Immunocytochemistry/Immunofluorescence: 5-HT2B Antibody [NBP1-90322] - Staining of human cell line SK-MEL-30 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322]

Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322]

Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322] - Staining of human endometrium shows moderate membranous positivity in glandular cells.
View 3 more images

Applications for 5-HT2B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: 5-HT2B

Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM]

Long Name

5-Hydroxytryptamine Receptor 2B

Alternate Names

5HT2B, HTR2B

Gene Symbol

HTR2B

Additional 5-HT2B Products

Product Documents for 5-HT2B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for 5-HT2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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