5-HT2B Products
5-HT2B is one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G protein-coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors, including 5-HT2B, mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele which blocks expression of 5-HTRB, and knockout studies in mice, suggest a role for 5-HT2B in impulsivity.
62 results for "5-HT2B" in Products
62 results for "5-HT2B" in Products
5-HT2B Products
5-HT2B is one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G protein-coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors, including 5-HT2B, mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele which blocks expression of 5-HTRB, and knockout studies in mice, suggest a role for 5-HT2B in impulsivity.
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Fluorescent serotonin 5HT2B receptor ligand for HTS
| Purity: | ≥95% (HPLC) |
Potent and selective 5-HT2B and 5-HT2C antagonist; orally active
| Chemical Name: | 3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride |
| Purity: | ≥99% (HPLC) |
D2-like agonist (D2>D3>D4)
| Chemical Name: | N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)ergoline-8-carboxamide |
| Purity: | ≥99% (HPLC) |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2880B |
| Applications: | Flow, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #1014838 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2880B |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322]](https://resources.bio-techne.com/images/products/5-HT2B-Antibody-Immunohistochemistry-Paraffin-NBP1-90322-img0011.jpg "Immunohistochemistry-Paraffin: 5-HT2B Antibody [NBP1-90322]")
Selective 5-HT2B antagonist
| Chemical Name: | 1-[(2-Chloro-3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indole hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent, selective 5-HT2B antagonist
| Chemical Name: | N-(1-Methyl-1H-indolyl-5-yl)-N''-(3-methyl-5-isothiazolyl)urea |
| Purity: | ≥99% (HPLC) |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥99% (HPLC) |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: 5-HT2B Antibody [NBP1-55429]](https://resources.bio-techne.com/images/products/5-HT2B-Antibody-Western-Blot-NBP1-55429-img0004.jpg "Western Blot: 5-HT2B Antibody [NBP1-55429]")
High affinity and selective 5-HT2B antagonist
| Alternate Names: | MT 500 |
| Chemical Name: | 4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Monkey, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, Func |
![Immunohistochemistry-Paraffin: 5-HT2B Antibody - BSA Free [NLS1111]](https://resources.bio-techne.com/images/products/5-HT2B-Antibody-Immunohistochemistry-Paraffin-NLS1111-img0006.jpg "Immunohistochemistry-Paraffin: 5-HT2B Antibody - BSA Free [NLS1111]")
High affinity 5-HT2B antagonist; orally active
| Chemical Name: | 1-[(3,4-Dimethoxyphenyl)methy]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indole hydrochloride |
| Purity: | ≥99% (HPLC) |
| Applications: | WB, ELISA, MA, AP, PAGE |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: 5-HT2B Antibody - BSA Free [NLS1187]](https://resources.bio-techne.com/images/products/5-HT2B-Antibody-Immunohistochemistry-Paraffin-NLS1187-img0008.jpg "Immunohistochemistry-Paraffin: 5-HT2B Antibody - BSA Free [NLS1187]")
Potent 5-HT2 antagonist
| Chemical Name: | 6-[2-[4-[Bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one |
| Purity: | ≥98% (HPLC) |
α partial agonist; also D2-like partial agonist and 5-HT antagonist
| Chemical Name: | 9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human 5-HT2B GST (N-Term) Protein [H00003357-P01]](https://resources.bio-techne.com/images/products/qc_test-H00003357-P01-1.jpg "SDS-PAGE: Recombinant Human 5-HT2B GST (N-Term) Protein [H00003357-P01]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4A4 |
| Applications: | WB, ELISA |
![Western Blot: 5-HT2B Antibody (4A4) [H00003357-M01-100ug]](https://resources.bio-techne.com/images/products/5-HT2B-Antibody-4A4-Western-Blot-H00003357-M01-100ug-img0002.jpg "Western Blot: 5-HT2B Antibody (4A4) [H00003357-M01-100ug]")
| Applications: | AC |
| Applications: | AC |