ALK/CD246 Antibody (7A11A4) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61845

Novus Biologicals, part of Bio-Techne
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NBP2-61845
NBP2-61845-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 7A11A4

Format

BSA Free

Concentration

1 mg/ml

View all ALK/CD246 Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human ALK/CD246 (AA: 1366-1468) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

26.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ALK/CD246 Antibody (7A11A4) - BSA Free

Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis using ALK mAb against human ALK (AA: 1366-1468) recombinant protein. (Expected MW is 36.9 kDa)
Immunocytochemistry/ Immunofluorescence: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

Immunocytochemistry/ Immunofluorescence: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

Immunocytochemistry/Immunofluorescence: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis of Hela cells using ALK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.
Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis using ALK mAb against HEK293 (1) and ALK (AA: 1366-1468)-hIgGFc transfected HEK293 (2) cell lysate.
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Applications for ALK/CD246 Antibody (7A11A4) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Immunocytochemistry/ Immunofluorescence

1:50-1:250

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALK/CD246

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).;

Long Name

Anaplastic Lymphoma Kinase

Alternate Names

CD246, Ki-1, Tcrz

Gene Symbol

ALK

Additional ALK/CD246 Products

Product Documents for ALK/CD246 Antibody (7A11A4) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ALK/CD246 Antibody (7A11A4) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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