ALK/CD246 Products
Anaplastic Lymphoma Kinase (ALK), also known as CD246, is a 220 kDa transmembrane glycoprotein that is primarily expressed in the developing nervous system. ALK contains one LDL Receptor (LDLR) class A domain, two meprin/A5-protein/PTPmu (MAM) domains, and a cytoplasmic kinase domain. Chromosomal translocation involving ALK and the nucleolar NPM protein result in a cytoplasmic fusion protein that exists as a dimer. The kinase domain in NPM-ALK is constitutively active and participates in cellular transformation. ALK translocations are found in a variety of tumors. Within the extracellular domain, human and mouse ALK share 88% amino acid sequence identity.
161 results for "ALK/CD246" in Products
161 results for "ALK/CD246" in Products
ALK/CD246 Products
Anaplastic Lymphoma Kinase (ALK), also known as CD246, is a 220 kDa transmembrane glycoprotein that is primarily expressed in the developing nervous system. ALK contains one LDL Receptor (LDLR) class A domain, two meprin/A5-protein/PTPmu (MAM) domains, and a cytoplasmic kinase domain. Chromosomal translocation involving ALK and the nucleolar NPM protein result in a cytoplasmic fusion protein that exists as a dimer. The kinase domain in NPM-ALK is constitutively active and participates in cellular transformation. ALK translocations are found in a variety of tumors. Within the extracellular domain, human and mouse ALK share 88% amino acid sequence identity.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #ALK/1503 |
| Applications: | WB, ICC/IF, Flow |
![Western Blot: ALK/CD246 Antibody (ALK/1503) [NBP2-53253]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-ALK-1503-Western-Blot-NBP2-53253-img0002.jpg "Western Blot: ALK/CD246 Antibody (ALK/1503) [NBP2-53253]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1504 |
| Applications: | IHC, ICC/IF, Flow |
![Immunohistochemistry-Paraffin: ALK/CD246 Antibody (ALK/1504) [NBP3-07771]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-ALK-1504-Immunohistochemistry-Paraffin-NBP3-07771-img0002.jpg "Immunohistochemistry-Paraffin: ALK/CD246 Antibody (ALK/1504) [NBP3-07771]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1031 |
| Applications: | WB |
![Western Blot: ALK/CD246 Antibody (ALK/1031) [NBP3-07748]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-ALK-1031-Western-Blot-NBP3-07748-img0001.jpg "Western Blot: ALK/CD246 Antibody (ALK/1031) [NBP3-07748]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1032 |
| Applications: | WB |
![Western Blot: ALK/CD246 Antibody (ALK/1032) [NBP3-07749]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-ALK-1032-Western-Blot-NBP3-07749-img0001.jpg "Western Blot: ALK/CD246 Antibody (ALK/1032) [NBP3-07749]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1504 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1504 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1031 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1031 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1032 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1032 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1504 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1032 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1031 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1031 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1031 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1504 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1032 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1504 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #ALK/1032 |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | Q9UM73.3 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #383625 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #383603 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #7A11A4 |
| Applications: | WB, ELISA, ICC/IF, Flow |
![Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]](https://resources.bio-techne.com/images/products/ALK-CD246-Antibody-7A11A4-Western-Blot-NBP2-61845-img0004.jpg "Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]")