The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Long Name

Bone Morphogenetic Protein Receptor IA/Activin Receptor-like Kinase 3

Alternate Names

ALK-3, BMPR1A, BMPRIA, CD292

Gene Symbol

BMPR1A

Additional BMPR-IA/ALK-3 Products

Product Documents for BMPR-IA/ALK-3 Antibody (002) [Alexa Fluor® 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for BMPR-IA/ALK-3 Antibody (002) [Alexa Fluor® 405]

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

BMPR-IA/ALK-3 Antibody (002) [Alexa Fluor® 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90398AF405

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

Concentration

View all BMPR-IA/ALK-3 Antibodies »

Product Summary for BMPR-IA/ALK-3 Antibody (002) [Alexa Fluor® 405]

Immunogen

Clonality

Host

Isotype

Applications for BMPR-IA/ALK-3 Antibody (002) [Alexa Fluor® 405]

ELISA

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: BMPR-IA/ALK-3