BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12029

Novus Biologicals, part of Bio-Techne
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NBP2-12029
NBP2-12029-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0053-8L7

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all BMPR-IA/ALK-3 Antibodies »

Product Summary for BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free

Immunogen

Human recombinant BMPR-IA/ALK-3 (extracellular domain)

Specificity

In Western blots, this antibody shows good cross-reactivity with mouse BMPR-IA/ALK-3, but no cross-reactivity with recombinant human BMPR-IB or rhBMPR-II.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free

Immunohistochemistry: BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free [NBP2-12029]

Immunohistochemistry: BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free [NBP2-12029]

Immunohistochemistry: BMPR-IA/ALK-3 Antibody (MM0053-8L7) [NBP2-12029] - Human placenta (formalin fixed and paraffin embedded) section is subjected to IHC.

Applications for BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BMPR-IA/ALK-3

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Long Name

Bone Morphogenetic Protein Receptor IA/Activin Receptor-like Kinase 3

Alternate Names

ALK-3, BMPR1A, BMPRIA, CD292

Gene Symbol

BMPR1A

UniProt

CAA80257

Additional BMPR-IA/ALK-3 Products

Product Documents for BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BMPR-IA/ALK-3 Antibody (MM0053-8L7) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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