BMPR-IB/ALK-6 Antibody (477914) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # FAB5051B

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

MAB5051

Alexa Fluor 532

FAB5051X

Allophycocyanin/Cy7

FAB5051APCCY7

CoraFluor 1

FAB5051CL1

DyLight 350

FAB5051D

DyLight 405

FAB5051E

DyLight 488

FAB5051K

DyLight 550

FAB5051L

DyLight 594

FAB5051M

DyLight 650

FAB5051W

DyLight 680

FAB5051Y

DyLight 755

FAB5051Z

FITC

FAB5051F

HRP

FAB5051H

Janelia Fluor 525

FAB5051JF525

Janelia Fluor 549

FAB5051I

Janelia Fluor 585

FAB5051JF585

Janelia Fluor 635

FAB5051JF635

Janelia Fluor 646

FAB5051J

Janelia Fluor 669

FAB5051JF669

mFluor Violet 450 SE

FAB5051MFV450

mFluor Violet 500 SE

FAB5051MFV500

mFluor Violet 610 SE

FAB5051MFV610

PE/Atto594

FAB5051PEATT594

PE/Cy5.5

FAB5051PECY55

PE/Cy7

FAB5051PECY7

PerCP

FAB5051C

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry

Label

Biotin

Antibody Source

Recombinant Monoclonal Mouse IgG_2B Clone # 477914

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BMPR-IB/ALK-6 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human BMPR‑IB/ALK‑6
Lys14-Arg126
Accession # O00238

Specificity

Detects human BMPR‑IB/ALK‑6 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse BMPR-IB is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Applications for BMPR-IB/ALK-6 Antibody (477914) [Biotin]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BMPR-IB/ALK-6

BMPR1B encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Long Name

Bone Morphogenetic Protein Receptor IB

Alternate Names

ALK-6, BMPR1B, BMPRIB, CDw293

Gene Symbol

BMPR1B

Additional BMPR-IB/ALK-6 Products

Product Documents for BMPR-IB/ALK-6 Antibody (477914) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for BMPR-IB/ALK-6 Antibody (477914) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews