BRCA2 Antibody (BRCA2/2158) [DyLight 680]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24027FR

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-23660

Alexa Fluor 350

NBP3-24027AF350

Alexa Fluor 405

NBP3-24027AF405

Alexa Fluor 488

NBP3-24027AF488

Alexa Fluor 532

NBP3-24027AF532

Alexa Fluor 594

NBP3-24027AF594

Alexa Fluor 647

NBP3-24027AF647

Alexa Fluor 700

NBP3-24027AF700

Alexa Fluor 750

NBP3-24027AF750

Allophycocyanin

NBP3-24027APC

Biotin

NBP3-24027B

CoraFluor 1

NBP3-24027CL1

DyLight 350

NBP3-24027UV

DyLight 405

NBP3-24027V

DyLight 488

NBP3-24027G

DyLight 550

NBP3-24027R

DyLight 594

NBP3-24027DL594

DyLight 650

NBP3-24027C

DyLight 755

NBP3-24027IR

FITC

NBP3-24027F

HRP

NBP3-24027H

Janelia Fluor 525

NBP3-24027JF525

Janelia Fluor 549

NBP3-24027JF549

Janelia Fluor 646

NBP3-24027JF646

Janelia Fluor 669

NBP3-24027JF669

mFluor Violet 450 SE

NBP3-24027MFV450

mFluor Violet 500 SE

NBP3-24027MFV500

mFluor Violet 610 SE

NBP3-24027MFV610

PE

NBP3-24027PE

PerCP

NBP3-24027PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-24027

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # BRCA2/2158

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BRCA2 Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 200-500) of human BRCA2 protein (exact sequence is proprietary)

Localization

Nucleus. Cytoplasm.

Marker

Breast Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for BRCA2 Antibody (BRCA2/2158) [DyLight 680]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BRCA2

BRCA 2 is localized to chromosome 13q12 - q13. Loss of heterozygosity of 13q is observed in 25% of sporadic breast tumors, which indicates that BRCA 2 might be a tumor suppressor gene. BRCA 2 confers only a low ovarian cancer risk. Reportedly, in MCF-10F (normal breast epithelial cell line) and MCF-7 (breast cancer cell line) cells the expression of BRCA 2 RNA lowers in G0 and early G1 phases then gets up-regulated at the G1 / S phase junction.

Long Name

Breast Cancer 2

Alternate Names

BRCA1/BRCA2-containing complex, subunit 2, BRCC2, breast and ovarian cancer susceptibility gene, early onset, breast cancer 2 tumor suppressor, breast cancer 2, early onset, breast cancer susceptibility protein BRCA2, breast cancer type 2 susceptibility protein, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1Fanconi anemia, complementation group D1, Fanconi anemia group D1 protein, GLM3, PNCA2

Gene Symbol

BRCA2

Additional BRCA2 Products

Product Documents for BRCA2 Antibody (BRCA2/2158) [DyLight 680]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for BRCA2 Antibody (BRCA2/2158) [DyLight 680]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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