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C-myc promoter-binding protein Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49444

Novus Biologicals, part of Bio-Techne
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NBP2-49444
NBP2-49444-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGL

Reactivity Notes

Mouse (84%), Rat (82%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for C-myc promoter-binding protein Antibody

Immunocytochemistry/ Immunofluorescence: C-myc promoter-binding protein Antibody [NBP2-49444]

Immunocytochemistry/ Immunofluorescence: C-myc promoter-binding protein Antibody [NBP2-49444]

Immunocytochemistry/Immunofluorescence: C-myc promoter-binding protein Antibody [NBP2-49444] - Staining of human cell line HaCaT shows localization to nucleus & nucleoli.
Immunohistochemistry-Paraffin: C-myc promoter-binding protein Antibody [NBP2-49444]

Immunohistochemistry-Paraffin: C-myc promoter-binding protein Antibody [NBP2-49444]

Immunohistochemistry-Paraffin: C-myc promoter-binding protein Antibody [NBP2-49444] - Staining of human bone marrow shows moderate nuclear positivity in hematopoietic cells.

Applications for C-myc promoter-binding protein Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: C-myc promoter-binding protein

DENND4A, also known as C-myc promoter-binding protein, consists of a 209.2 kDa and a 213.7 kDa isoform and is utilized in promoting the conversion of Rab proteins from their inactive GDP-bound form into their active GTP-bound form. This protein is currently being studied for involvement in prostatitis. In transcription pathways, the protein interacts with YWHAQ, YWHAZ, CEBPE, YWHAB, and YWHAG.

Alternate Names

c-myc promoter binding protein, C-myc promoter-binding protein, DENN domain-containing protein 4A, DENN/MADD domain containing 4A, IRLBFLJ33949, KIAA0476, MYCPBP

Gene Symbol

DENND4A

Additional C-myc promoter-binding protein Products

Product Documents for C-myc promoter-binding protein Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for C-myc promoter-binding protein Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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