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CA125/MUC16 Antibody (OTI2C4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46051

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2C4

Concentration

1 mg/ml

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 10329-10628 of human MUC16 (NP_078966) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CA125/MUC16 Antibody (OTI2C4)

Western Blot: CA125/MUC16 Antibody (OTI2C4) [NBP2-46051]

Western Blot: CA125/MUC16 Antibody (OTI2C4) [NBP2-46051]

Western Blot: CA125/MUC16 Antibody (OTI2C4) [NBP2-46051] - E.coli lysate (left lane) and E.coli lysate expressing Human recombinant protein fragment (right lane) corresponding to amino acids 10329-10628 of human MUC16 (NP_078966) were separated by SDS-PAGE and immunoblotted with MUC16.
Immunohistochemistry: CA125/MUC16 Antibody (OTI2C4) [NBP2-46051]

Immunohistochemistry: CA125/MUC16 Antibody (OTI2C4) [NBP2-46051]

Immunohistochemistry: CA125/MUC16 Antibody (OTI2C4) [NBP2-46051] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Applications for CA125/MUC16 Antibody (OTI2C4)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CA125/MUC16

MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators.

Long Name

Ovarian Cancer Antigen CA125

Alternate Names

MUC16

Gene Symbol

MUC16

UniProt

Additional CA125/MUC16 Products

Product Documents for CA125/MUC16 Antibody (OTI2C4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CA125/MUC16 Antibody (OTI2C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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