Cav1.3 Antibody (S48) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12893CL1

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP2-12893

Alexa Fluor 350

NBP2-12893AF350

Alexa Fluor 405

NBP2-12893AF405

Alexa Fluor 488

NBP2-12893AF488

Alexa Fluor 532

NBP2-12893AF532

Alexa Fluor 594

NBP2-12893AF594

Alexa Fluor 647

NBP2-12893AF647

Alexa Fluor 700

NBP2-12893AF700

Alexa Fluor 750

NBP2-12893AF750

Biotin

NBP2-12893B

DyLight 350

NBP2-12893UV

DyLight 405

NBP2-12893V

DyLight 488

NBP2-12893G

DyLight 550

NBP2-12893R

DyLight 594

NBP2-12893DL594

DyLight 650

NBP2-12893C

DyLight 680

NBP2-12893FR

DyLight 755

NBP2-12893IR

FITC

NBP2-12893F

HRP

NBP2-12893H

Janelia Fluor 525

NBP2-12893JF525

Janelia Fluor 549

NBP2-12893JF549

Janelia Fluor 585

NBP2-12893JF585

Janelia Fluor 635

NBP2-12893JF635

Janelia Fluor 646

NBP2-12893JF646

Janelia Fluor 669

NBP2-12893JF669

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Microarray, Western Blot

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # S48

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cav1.3 Antibodies »

Product Summary for Cav1.3 Antibody (S48) [CoraFluor™ 1]

Immunogen

Fusion protein amino acids 859-875 of rat Cav1.3

Localization

Membrane, Cell Membrane

Specificity

Detects approx 250 kDa. No cross-reactivity against Cav1.2.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Cav1.3 Antibody (S48) [CoraFluor™ 1]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Microarray

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Cav1.3

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Expressed in pancreatic islets and in brain, where it has been seen in hippocampus, basal ganglia, habenula and thalamus. No expression in skeletal muscle.

Long Name

Voltage-dependent L-type calcium channel subunit alpha-1D

Alternate Names

CACH3, CACN4, CACNA1D, CACNL1A2, CCHL1A2

Gene Symbol

CACNA1D

Additional Cav1.3 Products

Product Documents for Cav1.3 Antibody (S48) [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Cav1.3 Antibody (S48) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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