Key Product Details

Species Reactivity

Mouse

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunoprecipitation, Inhibition of T Cell Function

Label

Janelia Fluor 646

Antibody Source

Monoclonal Rat IgG2 Clone # AP-MAB0825

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD27 Ligand/TNFSF7 Antibodies »

Product Specifications

Immunogen

Mouse B lymphoma

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Applications for CD27 Ligand/TNFSF7/CD70 Antibody (AP-MAB0825) [Janelia Fluor® 646]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Inhibition of T Cell Function

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD27 Ligand/TNFSF7

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Alternate Names

CD70, TNFSF7

Gene Symbol

CD70

Additional CD27 Ligand/TNFSF7 Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD27 Ligand/TNFSF7/CD70 Antibody (AP-MAB0825) [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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