Key Product Details

Species Reactivity

Mouse

Applications

CyTOF-ready, ELISA, Flow Cytometry, Functional, Immunocytochemistry/ Immunofluorescence

Label

PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # TAN 1-7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD27 Ligand/TNFSF7 Antibodies »

Product Specifications

Immunogen

Recombinant mouse CD27 Ligand/TNFSF7/CD70 (extracellular domain, aa residues 41-195)

Specificity

This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [PE/Cy7]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: CD27 Ligand/TNFSF7

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Alternate Names

CD70, TNFSF7

Gene Symbol

CD70

Additional CD27 Ligand/TNFSF7 Products

Product Documents for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [PE/Cy7]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [PE/Cy7]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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