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CD42b/GPIb alpha Antibody (AK2) [PE/Cy7]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-63790PECY7

Clone AK2 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NB100-63790PECY7
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunoprecipitation

Label

PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # AK2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Made to Human CD42b

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:29437579).

Specificity

Recognises the human CD42b cell surface antigen, also known as platelet glycoprotein GP1B. CD42b is expressed by platelets and megakaryocytes. Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets (1).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for CD42b/GPIb alpha Antibody (AK2) [PE/Cy7]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: CD42b/GPIb alpha

CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.

Long Name

Glycoprotein lb [Platelet] alpha

Alternate Names

BP1BA, BSS, CD42b, GP1BA, GPIb alpha

Gene Symbol

GP1BA

Additional CD42b/GPIb alpha Products

Product Documents for CD42b/GPIb alpha Antibody (AK2) [PE/Cy7]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD42b/GPIb alpha Antibody (AK2) [PE/Cy7]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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