CDC2/CDK1 Antibody (CDK1/873) [DyLight 550]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11507R
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Bovine, Drosophila (Negative), Mink, Monkey, Mouse (Negative), Rat (Negative), S. pombe (Negative), Xenopus (Negative), Yeast (Negative)
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
DyLight 550 (Excitation = 562 nm, Emission = 576 nm)
Antibody Source
Monoclonal Mouse IgG2a Kappa Clone # CDK1/873
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for CDC2/CDK1 Antibody (CDK1/873) [DyLight 550]
Immunogen
Recombinant human full-length CDC2/CDK1 protein. (Uniprot: P06493)
Reactivity Notes
Does not react with Mouse, Rat, Xenopus, drosophila, S, pombe or S. cerevisiae.
Localization
Nuclear and Cytoplasmic
Specificity
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2a Kappa
Applications for CDC2/CDK1 Antibody (CDK1/873) [DyLight 550]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: CDC2/CDK1
Long Name
Cell Division Cycle 2/Cyclin-dependent Kinase 1
Alternate Names
CDK1
Gene Symbol
CDK1
Additional CDC2/CDK1 Products
Product Documents for CDC2/CDK1 Antibody (CDK1/873) [DyLight 550]
Product Specific Notices for CDC2/CDK1 Antibody (CDK1/873) [DyLight 550]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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