COX-2 Antibody (COX2/1941) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08272G

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-07251

Alexa Fluor 350

NBP3-08272AF350

Alexa Fluor 405

NBP3-08272AF405

Alexa Fluor 488

NBP3-08272AF488

Alexa Fluor 532

NBP3-08272AF532

Alexa Fluor 594

NBP3-08272AF594

Alexa Fluor 647

NBP3-08272AF647

Alexa Fluor 700

NBP3-08272AF700

Alexa Fluor 750

NBP3-08272AF750

Allophycocyanin

NBP3-08272APC

Biotin

NBP3-08272B

CoraFluor 1

NBP3-08272CL1

DyLight 350

NBP3-08272UV

DyLight 405

NBP3-08272V

DyLight 550

NBP3-08272R

DyLight 594

NBP3-08272DL594

DyLight 650

NBP3-08272C

DyLight 680

NBP3-08272FR

DyLight 755

NBP3-08272IR

FITC

NBP3-08272F

HRP

NBP3-08272H

Janelia Fluor 525

NBP3-08272JF525

Janelia Fluor 549

NBP3-08272JF549

Janelia Fluor 585

NBP3-08272JF585

Janelia Fluor 635

NBP3-08272JF635

Janelia Fluor 646

NBP3-08272JF646

Janelia Fluor 669

NBP3-08272JF669

PE

NBP3-08272PE

PerCP

NBP3-08272PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-08272

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # COX2/1941

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all COX-2 Antibodies »

Product Summary for COX-2 Antibody (COX2/1941) [DyLight 488]

Immunogen

Recombinant human COX-2 protein fragment (around aa 442-572) (exact sequence is proprietary) (Uniprot: P35354)

Localization

Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for COX-2 Antibody (COX2/1941) [DyLight 488]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: COX-2

COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Long Name

Cyclooxygenase 2

Alternate Names

COX2, PGHS-2, PHS-II, PTGS2

Gene Symbol

PTGS2

Additional COX-2 Products

Product Documents for COX-2 Antibody (COX2/1941) [DyLight 488]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for COX-2 Antibody (COX2/1941) [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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