CXCR1/IL-8RA Antibody (42705) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # FAB330B

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

MAB330

Alexa Fluor 532

FAB330X

Allophycocyanin/Cy7

FAB330APCCY7

CoraFluor 1

FAB330CL1

DyLight 350

FAB330D

DyLight 405

FAB330E

DyLight 488

FAB330K

DyLight 550

FAB330L

DyLight 594

FAB330M

DyLight 650

FAB330W

DyLight 680

FAB330Y

DyLight 755

FAB330Z

HRP

FAB330H

Janelia Fluor 525

FAB330JF525

Janelia Fluor 549

FAB330I

Janelia Fluor 585

FAB330JF585

Janelia Fluor 635

FAB330JF635

Janelia Fluor 646

FAB330J

Janelia Fluor 669

FAB330JF669

mFluor Violet 450 SE

FAB330MFV450

mFluor Violet 500 SE

FAB330MFV500

mFluor Violet 610 SE

FAB330MFV610

PE/Atto594

FAB330PEATT594

PE/Cy5.5

FAB330PECY55

PE/Cy7

FAB330PECY7

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

CyTOF-reported, Flow Cytometry, Immunohistochemistry, Neutralization

Label

Biotin

Antibody Source

Recombinant Monoclonal Mouse IgG_2A Clone # 42705

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CXCR1/IL-8RA Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RA
Met1-Leu350
Accession # AAA59159

Specificity

Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for CXCR1/IL-8RA Antibody (42705) [Biotin]

Application

Recommended Usage

CyTOF-reported

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CXCR1/IL-8RA

CXCR1, also known as IL-8 RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8 RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness.

Long Name

Interleukin 8 Receptor A

Alternate Names

CD181, IL-8 RA, IL8RA

Gene Symbol

CXCR1

Additional CXCR1/IL-8RA Products

Product Documents for CXCR1/IL-8RA Antibody (42705) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for CXCR1/IL-8RA Antibody (42705) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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