Cytokeratin 17 Antibody (KRT17/8320R) [CoraFluor™ 1]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20908CL1
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry-Paraffin
Label
CoraFluor 1
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # KRT17/8320R
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Cytokeratin 17 Antibody (KRT17/8320R) [CoraFluor™ 1]
Immunogen
Recombinant fragment of human Cytokeratin 17 protein (exact sequence is proprietary)
Localization
Cytoplasm.
Specificity
Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation CK17 is expressed in SCLC much higher than in LADC Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17 Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course Additionally, anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Applications for Cytokeratin 17 Antibody (KRT17/8320R) [CoraFluor™ 1]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark. Do not freeze.
Background: Cytokeratin 17
Long Name
Cytokeratin 17/KRT17
Alternate Names
CK-17, cytokeratin-17, K17, keratin 17, type I, keratin, type I cytoskeletal 17, PCHC1
Gene Symbol
KRT17
Additional Cytokeratin 17 Products
Product Documents for Cytokeratin 17 Antibody (KRT17/8320R) [CoraFluor™ 1]
Product Specific Notices for Cytokeratin 17 Antibody (KRT17/8320R) [CoraFluor™ 1]
CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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