DAP3 Antibody (42C617.1.2) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56539JF646

Novus Biologicals, part of Bio-Techne
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NB100-56539JF646
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Azide Free
NBP2-33222
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG Clone # 42C617.1.2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DAP3 Antibodies »

Product Specifications

Immunogen

The antibody was raised against a synthetic peptide corresponding to amino acids 51-66 of human DAP-3 protein.

Reactivity Notes

75% sequence identity with rat protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Applications for DAP3 Antibody (42C617.1.2) [Janelia Fluor® 646]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: DAP3

Death Associated Protein 3 (DAP3) is a 46 kDa protein carrying a potential nucleotide binding motif (P-loop) at its N-terminal region. The protein is widely expressed, and the expression is upregulated during membrane-receptor mediated apoptosis. In interferon-gamma and Fas induced apoptosis, DAP3 acts as a positive mediator by functioning downstream of the receptor signaling complex and upstream of the effector caspases. However, the mechanism for its function is largely unknown. Interestingly, the N-terminal 230 amino acid fragment of DAP3 alone protects cells from Fas induced cell death. The same region of DAP3 also serves as a binding site for the glucocorticoid receptor and mediates receptor functions.

Alternate Names

bMRP-10, DAP-3Death-associated protein 3, death associated protein 3, DKFZp686G12159,28S ribosomal protein S29, mitochondrial, FLJ12817, MGC126058, MGC126059, mitochondrial 28S ribosomal protein S29, MRP-S29Ionizing radiation resistance conferring protein, MRPS29S29mt

Gene Symbol

DAP3

Additional DAP3 Products

Product Documents for DAP3 Antibody (42C617.1.2) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DAP3 Antibody (42C617.1.2) [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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