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DDIT4L Antibody (DDIT-03)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62218

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow (Intracellular), Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # DDIT-03

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)

Specificity

The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for DDIT4L Antibody (DDIT-03)

Western Blot: DDIT4L Antibody (DDIT-03) [NBP2-62218]

Western Blot: DDIT4L Antibody (DDIT-03) [NBP2-62218]

Western Blot: DDIT4L Antibody (DDIT-03) [NBP2-62218] - Analysis of DDIT4L expression in HEK293-DDIT4L transfectants and HEK293 cells using mouse monoclonal antibody DDIT-03.

Applications for DDIT4L Antibody (DDIT-03)

Application
Recommended Usage

Flow (Intracellular)

1-4 ug/ml

Flow Cytometry

1-4 ug/ml

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.9% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DDIT4L

DDIT4L, also known as DNA damage-inducible transcript 4-like protein, is a 21.7 kDa 193 amino acid protein that regulates the TOR signaling pathway between the TSC1-TSC2 complex and AKT1, thus inhibiting cell growth. Current research is being conducted with diseases and disorders such as teratoma, melanoma, and hypoxia. The protein is involved in the TOR signaling pathway, where it interacts with SNRPG and PRKAB2.

Alternate Names

DNA damage-inducible transcript 4-like protein, DNA-damage-inducible transcript 4-like, HIF-1 responsive protein RTP801-like, homolog of mouse SMHS1, Protein regulated in development and DNA damage response 2, REDD-2, REDD2Rtp801L, regulated in development and DNA damage response 2, RTP801L

Gene Symbol

DDIT4L

Additional DDIT4L Products

Product Documents for DDIT4L Antibody (DDIT-03)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DDIT4L Antibody (DDIT-03)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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