DEPTOR/DEPDC6 Antibody [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49674G

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all DEPTOR/DEPDC6 Antibodies »

Product Specifications

Immunogen

A genomic peptide made to an internal region of the human DEPTOR protein (within residues 10-200).

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 31176743).

Localization

Intracellular.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for DEPTOR/DEPDC6 Antibody [DyLight 488]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: DEPTOR/DEPDC6

Deptor interacts with the mammalian target of rapamycin (mTOR), inhibiting kinase activities and ultimately negatively regulating the downstream mTOR pathways. Because of its critical role in signaling, changes in expression levels of Deptor can lead to hyperplasia, apoptosis, and several cancers. Deptor seems to lead to cytokine cascades that are important in endometriosis and the induction of labor. Through mTOR interactions, Deptor is implicated in pathways for cell growth and differentiation, as well as cell-cycle prolongation or termination.

Long Name

DEP Domain Containing mTOR-interacting Protein

Alternate Names

DEP.6, DEPDC6

Gene Symbol

DEPTOR

Additional DEPTOR/DEPDC6 Products

Product Documents for DEPTOR/DEPDC6 Antibody [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for DEPTOR/DEPDC6 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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