ERK5/BMK1 Antibody (OTI3H2) [PerCP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-71243PCP

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-03371

Alexa Fluor 350

NBP2-71243AF350

Alexa Fluor 405

NBP2-71243AF405

Alexa Fluor 488

NBP2-71243AF488

Alexa Fluor 532

NBP2-71243AF532

Alexa Fluor 594

NBP2-71243AF594

Alexa Fluor 647

NBP2-71243AF647

Alexa Fluor 700

NBP2-71243AF700

Alexa Fluor 750

NBP2-71243AF750

Allophycocyanin

NBP2-71243APC

Allophycocyanin/Cy7

NBP2-71243APCCY7

Biotin

NBP2-71243B

CoraFluor 1

NBP2-71243CL1

DyLight 350

NBP2-71243UV

DyLight 405

NBP2-71243V

DyLight 488

NBP2-71243G

DyLight 550

NBP2-71243R

DyLight 594

NBP2-71243DL594

DyLight 650

NBP2-71243C

DyLight 680

NBP2-71243FR

DyLight 755

NBP2-71243IR

FITC

NBP2-71243F

HRP

NBP2-71243H

Janelia Fluor 525

NBP2-71243JF525

Janelia Fluor 549

NBP2-71243JF549

Janelia Fluor 585

NBP2-71243JF585

Janelia Fluor 635

NBP2-71243JF635

Janelia Fluor 646

NBP2-71243JF646

Janelia Fluor 669

NBP2-71243JF669

mFluor Violet 450 SE

NBP2-71243MFV450

mFluor Violet 500 SE

NBP2-71243MFV500

mFluor Violet 610 SE

NBP2-71243MFV610

PE

NBP2-71243PE

PE/Atto594

NBP2-71243PEATT594

PE/Cy5.5

NBP2-71243PECY55

PE/Cy7

NBP2-71243PECY7

Forumulation

Catalog #

Azide and BSA Free

NBP2-71243

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

PerCP (Excitation = 490 nm, Emission = 675 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # OTI3H2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ERK5/BMK1 Antibodies »

Product Summary for ERK5/BMK1 Antibody (OTI3H2) [PerCP]

Immunogen

Full length recombinant protein of human ERK5/BMK1 (NP_002740) produced in HEK293T cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for ERK5/BMK1 Antibody (OTI3H2) [PerCP]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ERK5/BMK1

The extracellular signal-regulated kinase 5 (ERK5), also known as MAPK7 or big mitogen-activated protein kinase 1 (BMK1), is a member of the MAP kinase subfamily (1). ERK5 differs considerably from other MAPKs; it contains an unusually long carboxyl-terminal tail which might contribute to the regulation of its activity and/or localization. In response to extracellular signals, ERK5 translocates to the nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors (2). ERK5 also differs from other MAPKs in possessing a potent transcriptional activation domain which mediates protein-protein interactions with the myocyte enhancer factor 2 (MEF2) transcription factors (3). ERK5 is specifically activated by MAPK kinase 5 (MAP2K5/MEK5) and plays an important role in mammary epithelial proliferation, endothelial cell survival and normal embryonic development (4-5).

Long Name

Extracellular Signal-regulated Kinase 5

Alternate Names

BMK1, MAPK7

Gene Symbol

MAPK7

Additional ERK5/BMK1 Products

Product Documents for ERK5/BMK1 Antibody (OTI3H2) [PerCP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ERK5/BMK1 Antibody (OTI3H2) [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Reviews

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