FKBP12 Antibody (1E5-A12)

Novus Biologicals, part of Bio-Techne | Catalog # H00002280-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

ELISA, Functional, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1E5-A12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FKBP12 Antibodies »

Product Specifications

Immunogen

FKBP1A (AAH05147, 1 a.a. ~ 108 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE

Specificity

FKBP1A - FK506 binding protein 1A, 12kDa

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for FKBP12 Antibody (1E5-A12)

Western Blot: FKBP12 Antibody (1E5-A12) [H00002280-M01]

Western Blot: FKBP12 Antibody (1E5-A12) [H00002280-M01]

Western Blot: FKBP12 Antibody (1E5-A12) [H00002280-M01] - Analysis of FKBP1A expression in transfected 293T cell line by FKBP1A monoclonal antibody (M01), clone 1E5-A12.Lane 1: FKBP1A transfected lysate(12 KDa).Lane 2: Non-transfected lysate.
Western Blot: FKBP12 Antibody (1E5-A12) [H00002280-M01]

Western Blot: FKBP12 Antibody (1E5-A12) [H00002280-M01]

Western Blot: FKBP12 Antibody (1E5-A12) [H00002280-M01] - FKBP1A monoclonal antibody (M01), clone 1E5-A12 Analysis of FKBP1A expression in HL-60.
Sandwich ELISA: FKBP12 Antibody (1E5-A12) [H00002280-M01] - Detection limit for recombinant GST tagged FKBP1A is 3 ng/ml as a capture antibody.

Applications for FKBP12 Antibody (1E5-A12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FKBP12

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels including the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. There is evidence of multiple alternatively spliced transcript variants for this gene, but the full length nature of some variants has not been determined.

Long Name

12 kDa FK506 Binding Protein

Alternate Names

FKBP1a, PKC12, PPIASE

Entrez Gene IDs

2280 (Human)

Gene Symbol

FKBP1A

OMIM

186945 (Human)

UniProt

AAH05147 (Human)

Additional FKBP12 Products

Product Documents for FKBP12 Antibody (1E5-A12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FKBP12 Antibody (1E5-A12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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