Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse Clone # 6E8.2F5

Format

Azide and BSA Free

Concentration

1 mg/ml

View all FSHR Antibodies »

Product Summary for FSHR Antibody (6E8.2F5) - Azide and BSA Free

Immunogen

A synthetic peptide made to the human FSH R protein sequence (between residues 1-200). [Swiss-Prot P23945]

Reactivity Notes

Immunogen's sequence similarity with other species: Chicken and Duck (70%), Xenopus (71%).

Localization

Cell membrane, Cytoplasm

Clonality

Monoclonal

Host

Mouse

Scientific Data Images for FSHR Antibody (6E8.2F5) - Azide and BSA Free

Western Blot: FSHR Antibody (6E8.2F5)Azide and BSA Free [NBP2-80743]

Western Blot: FSHR Antibody (6E8.2F5)Azide and BSA Free [NBP2-80743]

Western Blot: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743] - WB analysis of (A) 15kDa partial recombinant Human FSHR protein and (B) lysate of HepG2 cells using FSH R antibody (clone 6E8.2F5) at 3ug/ml concentration. Image from the standard format of this antibody.
Immunohistochemistry-Paraffin: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743]

Immunohistochemistry-Paraffin: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743]

Immunohistochemistry-Paraffin: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human placenta using FSH R antibody (clone 6E8.2F5) at 5 ug/ml concentration. Image from the standard format of this antibody.
Immunohistochemistry-Paraffin: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743]

Immunohistochemistry-Paraffin: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743]

Immunohistochemistry-Paraffin: FSHR Antibody (6E8.2F5) - Azide and BSA Free [NBP2-80743] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human kidney using FSH R antibody (clone 6E8.2F5) at 5 ug/ml concentration. Image from the standard format of this antibody.
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Applications for FSHR Antibody (6E8.2F5) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

2-5 ug/ml

Immunohistochemistry-Paraffin

2-5 ug/ml

Western Blot

2-3 ug/ml
Application Notes
The canonical isoform of FSHR is 78.3 kDa, however, it undergoes processing via glycosylation and the glycosylated protein runs at higher than predicted molecular weight. Under non-reducing conditions, FSHR may form dimers via disulfide bond formation.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FSHR

Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common alpha subunit and a homologous but distinct beta subunit. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, follicle-stimulating hormone receptor (FSHR), the beta subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, post-translational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.

Long Name

Follicle Stimulating Hormone Receptor

Alternate Names

FSH R, LGR1, ODG1

Gene Symbol

FSHR

Additional FSHR Products

Product Documents for FSHR Antibody (6E8.2F5) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FSHR Antibody (6E8.2F5) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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