Galectin-8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87317

Novus Biologicals, part of Bio-Techne
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NBP1-87317
NBP1-87317-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Galectin-8 Antibodies »

Product Summary for Galectin-8 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASS

Reactivity Notes

Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Galectin-8 Antibody

Western Blot: Galectin-8 Antibody [NBP1-87317]

Western Blot: Galectin-8 Antibody [NBP1-87317]

Western Blot: Galectin-8 Antibody [NBP1-87317] - Analysis in human cell line SK-BR-3.
Immunohistochemistry-Paraffin: Galectin-8 Antibody [NBP1-87317]

Immunohistochemistry-Paraffin: Galectin-8 Antibody [NBP1-87317]

Immunohistochemistry-Paraffin: Galectin-8 Antibody [NBP1-87317] - Staining in human stomach shows strong cytoplasmic and membranous positivity in chief cells.
Western Blot: Galectin-8 Antibody [NBP1-87317]

Western Blot: Galectin-8 Antibody [NBP1-87317]

Western Blot: Galectin-8 Antibody [NBP1-87317] - Analysis in control (vector only transfected HEK293T lysate) and LGALS8 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Applications for Galectin-8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Galectin-8

Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Galectin-8, also known as prostate-specific membrane antigen (PCTA-1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cellmatrix interactions in a manner similar to the selectin subgroup of C-type lectins.

Alternate Names

GAL8, Galectin8, LGALS8, PCTA1

Gene Symbol

LGALS8

Additional Galectin-8 Products

Product Documents for Galectin-8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Galectin-8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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