Galectin-8: cDNA Clones
The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. Galectin-8, also known as prostate carcinoma tumor antigen 1 (PCTA1) in humans, is a tandem repeat-type galectin. Galectin-8 is highly expressed in lung carcinomas and certain forms of prostate carcinomas as well as other tumor cells. It binds to a subset of cell surface integrins to modulate ECM-integrin interactions. As a soluble ligand, Galectin-8 can inhibit cell adhesion. Immobilized Galectin-8, however, has also been shown to promote cell adhesion.
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2 results for "Galectin-8 cDNA Clones" in Products
2 results for "Galectin-8 cDNA Clones" in Products
Galectin-8: cDNA Clones
The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. Galectin-8, also known as prostate carcinoma tumor antigen 1 (PCTA1) in humans, is a tandem repeat-type galectin. Galectin-8 is highly expressed in lung carcinomas and certain forms of prostate carcinomas as well as other tumor cells. It binds to a subset of cell surface integrins to modulate ECM-integrin interactions. As a soluble ligand, Galectin-8 can inhibit cell adhesion. Immobilized Galectin-8, however, has also been shown to promote cell adhesion.
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