Geminin Antibody (GMNN/3665) [Janelia Fluor® 669]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14128JF669
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array
Label
Janelia Fluor 669
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # GMNN/3665
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant fragment of human Geminin protein (exact sequence is proprietary) (Uniprot: O75496)
Localization
Nuclear expression in highly proliferating cells
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Geminin Antibody (GMNN/3665) [Janelia Fluor® 669]
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Protein Array
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Geminin
Geminin prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during the G1 phase and accumulates during the S, G2, and M phases of mitosis. Geminin is then degraded during the metaphase-anaphase trasitio,n allowing replication to occur during subsequent cycles.
Geminin antibodies are useful tools for a variety of research including developmental embryology, stem cell differentiation, neuroscience, and DNA replication studies.
Alternate Names
Gem, geminin, geminin, DNA replication inhibitor, RP3-369A17.3
Gene Symbol
GMNN
Additional Geminin Products
Product Documents for Geminin Antibody (GMNN/3665) [Janelia Fluor® 669]
Product Specific Notices for Geminin Antibody (GMNN/3665) [Janelia Fluor® 669]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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