gp130/CD130 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88138

Novus Biologicals, part of Bio-Techne
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NBP1-88138
NBP1-88138-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all gp130 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (86%). Reactivity reported in scientific literature (PMID: 19396608)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for gp130/CD130 Antibody - BSA Free

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138]

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138]

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138]

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138]

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138] - Staining of human placenta shows cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138]

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138]

Immunohistochemistry-Paraffin: gp130/CD130 Antibody [NBP1-88138] - Staining of human plasma shows moderate positivity.
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Applications for gp130/CD130 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: gp130

CD130 is encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Long Name

Glycoprotein 130

Alternate Names

CD130, IL6ST

Gene Symbol

IL6ST

Additional gp130 Products

Product Documents for gp130/CD130 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for gp130/CD130 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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