Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HECTD1 Antibodies »

Product Summary for HECTD1 Antibody [DyLight 550]

Immunogen

The immunogen for this product maps to a region between residue 2100 and 2150 of human HECT Domain Containing 1 using the numbering given in entry AAP13073.1 (GeneID 25831).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for HECTD1 Antibody [DyLight 550]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot (Negative)

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HECTD1

The HECTD1 gene encodes a2, 610 amino acid long, 298 kDA E3 ubiquitin-protein ligase HECTD1 protein that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester. It then directly transmits the ubiquitin to targeted substrates and may be essential for development of the head mesenchyme and neural tube closure. HECTD1 interacts in interferon signaling and cytokine signaling in the immune system and is known to interact with various genes such as NME2, ERCC2, PITX2, CCNA2, and NME1-NME2. HECTD1 has been investigated in many diseases such as angelman syndrome, teratoma, carcinoma, malaria, and influenza.

Alternate Names

E3 ligase for inhibin receptor, E3 ubiquitin-protein ligase HECTD1, EC 6.3.2.-, EULIR, HECT domain containing 1, HECT domain-containing protein 1, KIAA1131FLJ38315

Gene Symbol

HECTD1

Additional HECTD1 Products

Product Documents for HECTD1 Antibody [DyLight 550]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for HECTD1 Antibody [DyLight 550]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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