Human APP/Protease Nexin II (Research Grade Aducanumab Biosimilar) Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB9710
Recombinant Monoclonal Antibody For Research Use Only
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, Flow Cytometry
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG1 Clone # Hu15
Product Specifications
Immunogen
Human APP/Protease Nexin II
Specificity
Detects human APP/Protease Nexin II based on Aducanumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Aducanumab.
This
product is for research use only.
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.
Scientific Data Images
Detection of APP/Protease Nexin II (Aducanumab) in Human PBMC by Flow Cytometry
Human peripheral blood mononuclear cells (PBMCs) were stained with (A) Human Anti-Human APP/Protease Nexin II (Aducanumab Biosimilar) Monoclonal Antibody (Catalog # MAB9710) or (B) no primary antibody, followed by APC-conjugated Anti-Human IgG Secondary Antibody (Catalog # F0135) and Mouse anti-Human CD14 PE-conjugated antibody (Catalog # FAB3832P). View our protocol for Staining Membrane-associated Proteins.Applications
Application
Recommended Usage
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
Flow Cytometry
0.25 µg/106 cells
Sample: Human peripheral blood mononuclear cells (PBMCs)
Sample: Human peripheral blood mononuclear cells (PBMCs)
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from cell culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: APP
Long Name
Amyloid Precursor Protein
Alternate Names
Amyloid beta, beta Amyloid, Protease Nexin II
Gene Symbol
APP
Additional APP Products
Product Specific Notices
For research use only
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