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Human CTLA-4 (Research Grade Ipilimumab Biosimilar) PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB9928P

Recombinant Monoclonal Antibody For Research Use Only
R&D Systems, part of Bio-Techne
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FAB9928P-100

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu111

Product Specifications

Immunogen

Human CTLA-4

Specificity

Detects Human CTLA-4 based on Ipilimumab therapeutic antibody.This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Ipilimumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images

Detection of CTLA-4 antibody in HEK293 Human cell line Transfected with Human CTLA-4 and eGFP antibody by Flow Cytometry.

Detection of CTLA-4 in HEK293 Human cell line Transfected with Human CTLA-4 and eGFP by Flow Cytometry.

HEK293 Human cell line transfected with (A) Human CTLA-4 or (B) irrelevant transfectants and eGFP was stained with Human Anti-Human CTLA-4 (Research Grade Ipilimumab Biosimilar) PE‑conjugated Monoclonal Antibody (Catalog # FAB9928P). View our protocol for Staining Membrane-associated Proteins.

Applications

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample:  HEK293 Human cell line Transfected with Human CTLA-4 and eGFP
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CTLA-4

Ipilimumab is a biosimilar directed against the extracellular domain of CTLA‑4. This product can be used flow cytometry or various assay formats to measure CTLA‑4 expression.

Long Name

Cytotoxic T-lymphocyte-associated Molecule 4

Alternate Names

CD152, CTLA4

Entrez Gene IDs

1493 (Human); 12477 (Mouse); 403696 (Canine); 102115124 (Cynomolgus Monkey)

Gene Symbol

CTLA4

Additional CTLA-4 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices

For research use only

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